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October 08.2025
2 Minutes Read

Navigating Legacy and Change: Patrick Soon-Shiong's Journey in Biotech and Media

Patrick Soon-Shiong smiling and thoughtful, close-up portrait

Patrick Soon-Shiong: A Biotech Pioneer with Complicated Proportions

Patrick Soon-Shiong, a South African-born American physician, has long fascinated the biotechnology world with his investments and innovations. Known for his complex legacy, initially as a highly skilled surgeon and later as a billionaire entrepreneur, Soon-Shiong is determined to revolutionize healthcare, particularly cancer treatment, with his biotechnology company ImmunityBio. However, his high-profile actions and decisions have drawn both praise and criticism.

Foundations of a Fortune

Starting his career as a leading surgeon specializing in diabetes treatments, Soon-Shiong developed the revolutionary islet cell transplant, which aimed to replace damaged cells in diabetic patients. His commercial relationships, notably with prominent figures like car magnate Lee Iacocca, spurred him into the business world. After transitioning from academic to entrepreneurial pursuits, he founded APP Pharmaceuticals and Abraxis Bioscience. These ventures eventually led to lucrative sales of his companies, laying the groundwork for what would become a $20.8 billion empire.

Investment in Change: The Case of ImmunityBio

Despite victories, Soon-Shiong’s immunotherapy firm ImmunityBio has faced significant hurdles. A major drop in company valuation was triggered by a public offering priced below expectations and regulatory setbacks with the FDA. For many, these issues overshadow his contributions to cancer treatments, fueling frustrations among investors as they await approval for upcoming therapies. His recent fundraising efforts signify his commitment but also highlight the pressure mounting from the competitive biotech arena with the proliferation of COVID-19 vaccines further complicating the landscape.

Media Ventures and Community Impact

A pivotal moment in Soon-Shiong's career occurred in 2018 with his acquisition of the Los Angeles Times. While this purchase appeared to signify a passion for journalism and communication, the newspaper has faced financial struggles and layoffs under his ownership. Initiatives like the hiring of diverse journalists following discussions on equity reveal his intent to improve the legacy of the paper. Still, a dip in subscriptions and questionable editorial decisions have stirred concerns about the sustainability of his vision for local journalism.

Looking Ahead: Innovation and Controversy

Patrick Soon-Shiong continues to navigate an intricate path, trying to shape the future of health and media while facing scrutiny. As technology and medicine evolve, his potential to change lives hinges not only on his investments but also on addressing public concerns about his conduct in business and philanthropy. Soon-Shiong's constant juggling act between innovation and reputation will define not just his legacy but the communities impacted by his ventures.

Conclusion: A Legacy in the Balance

As Soon-Shiong attempts to lead in the competitive fields of biotechnology and media, his future is emblematic of the broader challenges facing business leaders today. The balance between ambition, ethics, and community engagement remains precarious, raising questions regarding transparency in an increasingly complex world.

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